OCC-1 (overexpressed in colon carcinoma-1) is a protein, which in humans is encoded by the gene C12orf75. The gene is approximately 40,882 bp long and encodes 63 amino acids. OCC-1 is ubiquitously expressed throughout the human body. OCC-1 has shown to be overexpressed in various colon carcinomas.Novel splice variant of this gene was also detected in various human cancer types; in addition to encoding a novel smaller protein (51 amino acids), OCC-1 gene produces a non-protein coding RNA splice variant lncRNA (called OCC-D variant).
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