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Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ←→ XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other activities include cell proliferat

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  • Une nucléoside diphosphate kinase (NDK, aussi NDPK) est une phosphotransférase qui catalyse la réaction : ATP + nucléoside diphosphate ADP + nucléoside triphosphate. Ces enzymes catalysent l'échange d'un groupe phosphate entre différents nucléosides diphosphates. Comme le cycle de Krebs ne produit que de l'ATP, la nucléotide diphosphate kinase permet de maintenir un équilibre entre les concentrations des différents nucléosides triphosphates. (fr)
  • Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ←→ XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other activities include cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor, endocytosis, and gene expression. (en)
  • Nukleosiddifosfatkinas är ett enzym som katalyserar överföringen av en fosfatgrupp från guanosintrifosfat (GTP) till adenosindifosfat (ADP), vilket genererar adenosintrifosfat (ATP). Detta är ett sätt att omvandla det GTP som bildas i citronsyracykeln till ATP. Nettoreaktion: GTP + ADP → GDP + ATP (sv)
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  • Nucleoside-diphosphate kinase (en)
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  • Une nucléoside diphosphate kinase (NDK, aussi NDPK) est une phosphotransférase qui catalyse la réaction : ATP + nucléoside diphosphate ADP + nucléoside triphosphate. Ces enzymes catalysent l'échange d'un groupe phosphate entre différents nucléosides diphosphates. Comme le cycle de Krebs ne produit que de l'ATP, la nucléotide diphosphate kinase permet de maintenir un équilibre entre les concentrations des différents nucléosides triphosphates. (fr)
  • Nukleosiddifosfatkinas är ett enzym som katalyserar överföringen av en fosfatgrupp från guanosintrifosfat (GTP) till adenosindifosfat (ADP), vilket genererar adenosintrifosfat (ATP). Detta är ett sätt att omvandla det GTP som bildas i citronsyracykeln till ATP. Nettoreaktion: GTP + ADP → GDP + ATP (sv)
  • Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ←→ XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other activities include cell proliferat (en)
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  • Nucléoside diphosphate kinase (fr)
  • Nucleoside-diphosphate kinase (en)
  • Nukleosiddifosfatkinas (sv)
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  • Nucleoside-diphosphate kinase (en)
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