About: Nick (DNA)

An Entity of Type: disease, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands.

Property Value
dbo:abstract
  • A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands. (en)
  • Une césure, ou coupure simple brin, ou coupure haplotomique, ou cassure d'un brin, est la coupure d'une liaison phosphodiester entre deux nucléotides adjacents sur un des deux brins d'acide nucléique. Dans le génie génétique, ou lors de mutations, la césure est un mécanisme qui permet l'insertion d'une séquence de nucléotides, ou élément transposable ou transposon, dans le génome de la cellule hôte. * Portail de la biologie cellulaire et moléculaire (fr)
dbo:thumbnail
dbo:wikiPageID
  • 2892265 (xsd:integer)
dbo:wikiPageLength
  • 14828 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1066273133 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand typically through damage or enzyme action. Nicks allow DNA strands to untwist during replication, and are also thought to play a role in the DNA mismatch repair mechanisms that fix errors on both the leading and lagging daughter strands. (en)
  • Une césure, ou coupure simple brin, ou coupure haplotomique, ou cassure d'un brin, est la coupure d'une liaison phosphodiester entre deux nucléotides adjacents sur un des deux brins d'acide nucléique. Dans le génie génétique, ou lors de mutations, la césure est un mécanisme qui permet l'insertion d'une séquence de nucléotides, ou élément transposable ou transposon, dans le génome de la cellule hôte. * Portail de la biologie cellulaire et moléculaire (fr)
rdfs:label
  • Césure (génétique) (fr)
  • ニック (DNA) (ja)
  • Nick (DNA) (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageDisambiguates of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License