About: Neuroprotectin

An Entity of Type: Thing, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Neuroprotectin D1 (NPD1) (10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid) also known as Protectin D1 (PD1) is a docosanoid derived from the polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA), which is a component of fish oil and the most important omega-3 PUFA. Like other members of the specialized proresolving mediators class of PUFA metabolites, NPD1 exerts potent anti-inflammatory and anti-apoptotic/neuroprotective bioactivity. Other neuroprotectins with similar activity include: PDX (10R,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid); 20-hydroxy-PD1 (10R,17S,20-trihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid); and 10-epi-PD1 (10R,17S-Dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid). The activity of neuroprotectin-like metabolite, 17-epi-PD1

Property Value
dbo:abstract
  • Neuroprotectin D1 (NPD1) (10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid) also known as Protectin D1 (PD1) is a docosanoid derived from the polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA), which is a component of fish oil and the most important omega-3 PUFA. Like other members of the specialized proresolving mediators class of PUFA metabolites, NPD1 exerts potent anti-inflammatory and anti-apoptotic/neuroprotective bioactivity. Other neuroprotectins with similar activity include: PDX (10R,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid); 20-hydroxy-PD1 (10R,17S,20-trihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid); and 10-epi-PD1 (10R,17S-Dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid). The activity of neuroprotectin-like metabolite, 17-epi-PD1 (10R,17R-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid), has not yet been reported. Neuroprotectins A and B, which are bicyclohexapeptides, are to be distinguished structurally and mechanistically from the neuroprotectin D's. (en)
dbo:wikiPageID
  • 13986656 (xsd:integer)
dbo:wikiPageLength
  • 3516 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1120102353 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdfs:comment
  • Neuroprotectin D1 (NPD1) (10R,17S-dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid) also known as Protectin D1 (PD1) is a docosanoid derived from the polyunsaturated fatty acid (PUFA) docosahexaenoic acid (DHA), which is a component of fish oil and the most important omega-3 PUFA. Like other members of the specialized proresolving mediators class of PUFA metabolites, NPD1 exerts potent anti-inflammatory and anti-apoptotic/neuroprotective bioactivity. Other neuroprotectins with similar activity include: PDX (10R,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid); 20-hydroxy-PD1 (10R,17S,20-trihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid); and 10-epi-PD1 (10R,17S-Dihydroxy-4Z,7Z,11E,13E,15Z,19Z-docosahexaenoic acid). The activity of neuroprotectin-like metabolite, 17-epi-PD1 (en)
rdfs:label
  • Neuroprotectin (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License