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Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of the approved drug belantamab mafodotin in multiple myeloma and some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.

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  • Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of the approved drug belantamab mafodotin in multiple myeloma and some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. (en)
  • モノメチルアウリスタチンF(Monomethyl auristatin F;MMAF)は、合成抗悪性腫瘍剤である。多発性骨髄腫治療薬のや、、等一部の実験的抗がん抗体薬物複合体の一部をなす。MMAF-MAB-複合体の国際一般名では、MMAFに抗体との結合構造(下記参照)を加えたものをマホドチン(mafodotin)という。 (ja)
dbo:iupacName
  • (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid (en)
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  • Monomethylauristatin F.svg (en)
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  • Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of the approved drug belantamab mafodotin in multiple myeloma and some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. (en)
  • モノメチルアウリスタチンF(Monomethyl auristatin F;MMAF)は、合成抗悪性腫瘍剤である。多発性骨髄腫治療薬のや、、等一部の実験的抗がん抗体薬物複合体の一部をなす。MMAF-MAB-複合体の国際一般名では、MMAFに抗体との結合構造(下記参照)を加えたものをマホドチン(mafodotin)という。 (ja)
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  • モノメチルアウリスタチンF (ja)
  • Monomethyl auristatin F (en)
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