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- Lonaprisan (INN, USAN) (developmental code names ZK-230211, BAY 86-5044, ZK-PRA) is a synthetic, steroidal antiprogestogen which was under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis, dysmenorrhea, and breast cancer but was discontinued. It is a potent and highly selective silent antagonist of the progesterone receptor (PR). The drug reached phase II clinical trials prior to its discontinuation. (en)
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- 4243 (xsd:nonNegativeInteger)
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- CCC1=CC=C[C@H]2C[C@]3C (en)
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- VHZPUDNSVGRVMB-RXDLHWJPSA-N (en)
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- ZK-230211; BAY 86-5044; ZK-PRA; 11β--17β-hydroxy-17α-estra-4,9-dien-3-one (en)
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- Lonaprisan (INN, USAN) (developmental code names ZK-230211, BAY 86-5044, ZK-PRA) is a synthetic, steroidal antiprogestogen which was under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis, dysmenorrhea, and breast cancer but was discontinued. It is a potent and highly selective silent antagonist of the progesterone receptor (PR). The drug reached phase II clinical trials prior to its discontinuation. (en)
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