Jacob Ezekiel (June 28, 1812 – May 16, 1899) was an American merchant and leader of the Jewish community in antebellum Richmond, Virginia. In Cincinnati after the Civil War, he was for many years Secretary of the Board of Hebrew Union College. He was a charter member of B'nai B'rith, the first national Jewish organization in the United States. According to his son Moses, he was a good writer and a well-read man, "a man of cultivation", who possessed the complete works of Maimonides. He was the father of Moses Jacob Ezekiel (1844–1917), who became America's most famous sculptor.