A guanylate cyclase activator (or "GUCA") is one of group of proteins which upregulates guanylate cyclase. It is also known as guanylate cyclase-activating protein, with the abbreviation "GCAP". Mutations can be associated with vision defects. There are five genes involved: * GUCA1A, GUCA1B, GUCA1C * GUCA2A, GUCA2B
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