An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Gantacurium chloride (formerly recognized as GW280430A and as AV430A) is a new experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.Gantacurium is not yet available for widespread clinical use: it is currently undergoing Phase III clinical development.

Property Value
dbo:abstract
  • Gantacurium chloride (formerly recognized as GW280430A and as AV430A) is a new experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.Gantacurium is not yet available for widespread clinical use: it is currently undergoing Phase III clinical development. (en)
dbo:bioavailability
  • 100.000000 (xsd:float)
dbo:casNumber
  • 213998-46-0
dbo:fdaUniiCode
  • LEY8QK99UR
dbo:pubchem
  • 10772467
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dbp:bioavailability
  • 100.0
dbp:c
  • 53 (xsd:integer)
dbp:casNumber
  • 213998 (xsd:integer)
dbp:chemspiderid
  • 8947782 (xsd:integer)
dbp:cl
  • 3 (xsd:integer)
dbp:eliminationHalfLife
  • unknown (en)
dbp:excretion
  • renal / hepatic (en)
dbp:h
  • 69 (xsd:integer)
dbp:iupacName
  • 4 (xsd:integer)
dbp:metabolism
  • rapid inactivation by endogenous cysteine adduct formation followed by slow ester hydrolysis (en)
dbp:n
  • 2 (xsd:integer)
dbp:o
  • 14 (xsd:integer)
dbp:proteinBound
  • unknown (en)
dbp:pubchem
  • 10772467 (xsd:integer)
dbp:routesOfAdministration
  • IV (en)
dbp:smiles
  • C[N@+]1CCCOC/C/Cl.[Cl-].[Cl-] (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:unii
  • LEY8QK99UR (en)
dbp:verifiedfields
  • changed (en)
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  • Gantacurium chloride (formerly recognized as GW280430A and as AV430A) is a new experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.Gantacurium is not yet available for widespread clinical use: it is currently undergoing Phase III clinical development. (en)
rdfs:label
  • Gantacurium chloride (en)
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