An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Forsythoside B is a natural product from the phenylpropanoid glycoside group, which is found in a number of plant species such as , Phlomis armeniaca, , Phlomoides tuberosa, , and Teucrium chamaedrys, several of which are used in Chinese traditional medicine in preparations such as Shuanghuanglian (双黄连). It acts as an inhibitor of inflammatory mediators such as TNF-alpha, IL-6, IκB and NF-κB, as well as the temperature sensitive channel TRPV3, but also activates the RhoA/ROCK signaling pathway which can cause hypersensitivity reactions when it is injected intravenously.

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dbo:abstract
  • Forsythoside B is a natural product from the phenylpropanoid glycoside group, which is found in a number of plant species such as , Phlomis armeniaca, , Phlomoides tuberosa, , and Teucrium chamaedrys, several of which are used in Chinese traditional medicine in preparations such as Shuanghuanglian (双黄连). It acts as an inhibitor of inflammatory mediators such as TNF-alpha, IL-6, IκB and NF-κB, as well as the temperature sensitive channel TRPV3, but also activates the RhoA/ROCK signaling pathway which can cause hypersensitivity reactions when it is injected intravenously. (en)
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  • 81525-13-5
dbo:pubchem
  • 23928102
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  • 81525 (xsd:integer)
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  • [-2-[[-3,4-dihydroxy-4-oxolan-2-yl]oxymethyl]-6-[2-ethoxy]-5-hydroxy-4-[-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] -3-prop-2-enoate (en)
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  • Forsythoside B is a natural product from the phenylpropanoid glycoside group, which is found in a number of plant species such as , Phlomis armeniaca, , Phlomoides tuberosa, , and Teucrium chamaedrys, several of which are used in Chinese traditional medicine in preparations such as Shuanghuanglian (双黄连). It acts as an inhibitor of inflammatory mediators such as TNF-alpha, IL-6, IκB and NF-κB, as well as the temperature sensitive channel TRPV3, but also activates the RhoA/ROCK signaling pathway which can cause hypersensitivity reactions when it is injected intravenously. (en)
rdfs:label
  • Forsythoside B (en)
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