About: Devazepide

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCKA receptor.

Property Value
dbo:abstract
  • Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCKA receptor. (en)
  • La devazepide è uno psicofarmaco della categoria delle benzodiazepine, ma con azioni abbastanza diverse dalla maggior parte delle benzodiazepine, privo di affinità per i recettori GABA A e agisce invece come antagonista del recettore CCK A (it)
dbo:casNumber
  • 103420-77-5
dbo:chEMBL
  • 9506
dbo:fdaUniiCode
  • JE6P7QY7NH
dbo:kegg
  • D02693
dbo:pubchem
  • 443375
dbo:thumbnail
dbo:wikiPageID
  • 20252095 (xsd:integer)
dbo:wikiPageLength
  • 5624 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1121932670 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • none (en)
dbp:c
  • 25 (xsd:integer)
dbp:casNumber
  • 103420 (xsd:integer)
dbp:chembl
  • 9506 (xsd:integer)
dbp:chemspiderid
  • 391607 (xsd:integer)
dbp:h
  • 20 (xsd:integer)
dbp:iupacName
  • N--1H-indole-2-carboxamide (en)
dbp:iupharLigand
  • 878 (xsd:integer)
dbp:kegg
  • D02693 (en)
dbp:n
  • 4 (xsd:integer)
dbp:o
  • 2 (xsd:integer)
dbp:pubchem
  • 443375 (xsd:integer)
dbp:smiles
  • O=CN[C@H]3/N=Cc5ccccc5 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • NFHRQQKPEBFUJK-HSZRJFAPSA-N (en)
dbp:unii
  • JE6P7QY7NH (en)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 405810511 (xsd:integer)
dbp:watchedfields
  • changed (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCKA receptor. (en)
  • La devazepide è uno psicofarmaco della categoria delle benzodiazepine, ma con azioni abbastanza diverse dalla maggior parte delle benzodiazepine, privo di affinità per i recettori GABA A e agisce invece come antagonista del recettore CCK A (it)
rdfs:label
  • Devazepide (en)
  • Devazepide (it)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License