About: Cinnamycin

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Cinnamycin is a tetracyclic antibacterial peptide produced by Streptomyces cinnamoneus containing 19 amino acid residues including the unusual amino acids threo-3-methyl-lanthionine, meso-lanthionine, , and 3-hydroxyaspartic acid. Cinnamycin belongs to the class of molecules known as lantibiotics which belongs to ribosomally synthesized post-translationally modified peptides. The unique receptor for cinnamycin is phosphatidylethanolamine (PE) lipids which is a major compound present in many bacterial cell membranes.

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  • Cinnamycin is a tetracyclic antibacterial peptide produced by Streptomyces cinnamoneus containing 19 amino acid residues including the unusual amino acids threo-3-methyl-lanthionine, meso-lanthionine, , and 3-hydroxyaspartic acid. Cinnamycin belongs to the class of molecules known as lantibiotics which belongs to ribosomally synthesized post-translationally modified peptides. The unique receptor for cinnamycin is phosphatidylethanolamine (PE) lipids which is a major compound present in many bacterial cell membranes. Cinnamycin was first isolated in 1952 and some other compounds with similar sequence and structure were found later. (en)
dbo:alternativeName
  • Lanthiopeptin; NSC-71936; Ro09-198 (en)
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  • (1S,4S,13S,16S,19R,22S,25S,28R,31S,37S,41R,44R,47S,50S,53R,56R,65S)-44-amino-37-(2-amino-2-oxoethyl)-50-(3-amino-3-oxopropyl)-4,16,22-tribenzyl-47-(3-carbamimidamidopropyl)-31-[(R)-carboxy(hydroxy)methyl]-41,70-dimethyl-2,5,8,14,17,20,23,26,29,32,35,38,45,48,51,54,57,67-octadecaoxo-25-propan-2-yl-42,69,72-trithia-3,6,9,15,18,21,24,27,30,33,36,39,46,49,52,55,58,60,66-nonadecazapentacyclo[38.18.9.319,56.328,53.09,13]triheptacontane-65-carboxylic acid (en)
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  • 1117577174 (xsd:integer)
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  • Cinnamycin.svg (en)
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  • 250 (xsd:integer)
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  • -44 (xsd:integer)
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  • Lanthiopeptin; NSC-71936; Ro09-198 (en)
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  • Cinnamycin is a tetracyclic antibacterial peptide produced by Streptomyces cinnamoneus containing 19 amino acid residues including the unusual amino acids threo-3-methyl-lanthionine, meso-lanthionine, , and 3-hydroxyaspartic acid. Cinnamycin belongs to the class of molecules known as lantibiotics which belongs to ribosomally synthesized post-translationally modified peptides. The unique receptor for cinnamycin is phosphatidylethanolamine (PE) lipids which is a major compound present in many bacterial cell membranes. (en)
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  • Cinnamycin (en)
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