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Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding cinnamaldehyde, utilizing NADPH and H+ and releasing free CoA and NADP+ in the process. Common biologically relevant cinnamoyl-CoA substrates for CCR include p-coumaroyl-CoA and feruloyl-CoA, which are converted into p-coumaraldehyde and coniferaldehyde, respectively, though most CCRs show activity toward a variety of other substituted cinnamoyl-CoA's as well. Catalyzing the first committed step in monolignol biosynthesis, this enzyme plays a critical role in lignin formation, a process important in plants both for structural development

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dbo:abstract
  • Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding cinnamaldehyde, utilizing NADPH and H+ and releasing free CoA and NADP+ in the process. Common biologically relevant cinnamoyl-CoA substrates for CCR include p-coumaroyl-CoA and feruloyl-CoA, which are converted into p-coumaraldehyde and coniferaldehyde, respectively, though most CCRs show activity toward a variety of other substituted cinnamoyl-CoA's as well. Catalyzing the first committed step in monolignol biosynthesis, this enzyme plays a critical role in lignin formation, a process important in plants both for structural development and defense response. (en)
  • La cinnamoil-CoA reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: cinnamaldeide + CoA + NADP+ ⇄ + NADPH + H+ L'enzima agisce anche su un grande numero di esteri cinnamoilici del coenzima A. (it)
  • シンナモイルCoAレダクターゼ(cinnamoyl-CoA reductase)は、フェニルプロパノイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 シンナムアルデヒド + CoA + NADP+ シンナモイルCoA + NADPH + H+ 反応式の通り、この酵素の基質はシンナムアルデヒドと補酵素AとNADP+、生成物はシンナモイルCoAとNADPHとH+である。 組織名はcinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)で、別名にferuloyl-CoA reductase, cinnamoyl-coenzyme A reductase, ferulyl-CoA reductase, feruloyl coenzyme A reductase, p-hydroxycinnamoyl coenzyme A reductase, cinnamoyl-CoA:NADPH reductaseがある。 (ja)
dbo:ecNumber
  • 1.2.1.44
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  • 14132613 (xsd:integer)
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  • 20092 (xsd:nonNegativeInteger)
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  • 1040525801 (xsd:integer)
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dbp:caption
  • Tertiary structure of CCR1 from Petunia x hybrida colored by secondary structural element, generated from 4R1S (en)
dbp:casNumber
  • 59929 (xsd:integer)
dbp:ecNumber
  • 1.200000 (xsd:double)
dbp:goCode
  • 16621 (xsd:integer)
dbp:iubmbEcNumber
  • 1 (xsd:integer)
dbp:name
  • Cinnamoyl-CoA reductase (en)
  • cinnamoyl-CoA reductase (en)
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rdfs:comment
  • La cinnamoil-CoA reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: cinnamaldeide + CoA + NADP+ ⇄ + NADPH + H+ L'enzima agisce anche su un grande numero di esteri cinnamoilici del coenzima A. (it)
  • シンナモイルCoAレダクターゼ(cinnamoyl-CoA reductase)は、フェニルプロパノイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 シンナムアルデヒド + CoA + NADP+ シンナモイルCoA + NADPH + H+ 反応式の通り、この酵素の基質はシンナムアルデヒドと補酵素AとNADP+、生成物はシンナモイルCoAとNADPHとH+である。 組織名はcinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)で、別名にferuloyl-CoA reductase, cinnamoyl-coenzyme A reductase, ferulyl-CoA reductase, feruloyl coenzyme A reductase, p-hydroxycinnamoyl coenzyme A reductase, cinnamoyl-CoA:NADPH reductaseがある。 (ja)
  • Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding cinnamaldehyde, utilizing NADPH and H+ and releasing free CoA and NADP+ in the process. Common biologically relevant cinnamoyl-CoA substrates for CCR include p-coumaroyl-CoA and feruloyl-CoA, which are converted into p-coumaraldehyde and coniferaldehyde, respectively, though most CCRs show activity toward a variety of other substituted cinnamoyl-CoA's as well. Catalyzing the first committed step in monolignol biosynthesis, this enzyme plays a critical role in lignin formation, a process important in plants both for structural development (en)
rdfs:label
  • Cinnamoyl-CoA reductase (en)
  • Cinnamoil-CoA reduttasi (it)
  • シンナモイルCoAレダクターゼ (ja)
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  • cinnamoyl-CoA reductase (en)
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