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Brei Holm is a tiny tidal islet in the western Shetland Islands. It is due east of Papa Stour, to which it is connected at low tide, just outside . It is about a mile off Mainland, Shetland, and not far from the Maiden Stack. It was a leper colony until the 18th century, but it has been suggested that many of the "lepers" there were suffering from a vitamin deficiency and not from leprosy at all.
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