BioGRID

The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions created in 2003 (originally referred to as simply the General Repository for Interaction Datasets by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital. It strives to provide a comprehensive resource of protein–protein interactions for all major species while attempting to remove redundancy to create a single mapping of protein interactions. Users of The BioGRID can search for their protein of interest and retrieve annotation, as well as physical and genetic interaction data as reported, by the primary literature and compiled by in house large scale curation efforts. The BioGRID is hosted in Toronto, Ontario, Canada and is partnered with the Saccharomyces Genome Database.