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- L'àcid bempedoic, comercialitzat com a Nexletol o Nustendi, és un fàrmac per al tractament de l'hipercolesterolèmia (nivells de colesterol de sang elevats). Els efectes secundaris més comuns inclouen hiperuricèmia (nivells elevats d'àcid úric en sang), dolor a les extremitats, i anèmia (baix recompte d'eritròcits). L'àcid bempedoic bloqueja un enzim hepàtic, l'adenosintrifosfat-citrat-liasa, involucrat en la síntesi del colesterol. L'àcid va ser aprovat per al seu ús en humans als Estats Units al febrer del 2020, i a la Unió Europea a l'abril del 2020. La U.S. Food and Drug Administration (FDA) el considera el primer fàrmac de la seva classe. (ca)
- Bempedoic acid, sold under the brand name Nexletol among others, is a medication for the treatment of hypercholesterolemia (high blood cholesterol levels). The most common side effects include hyperuricemia (high blood levels of uric acid), pain in arms or legs, and anemia (low red blood cell counts). Bempedoic acid blocks an enzyme in the liver called adenosine triphosphate-citrate lyase, which is involved in making cholesterol. Bempedoic acid was approved for use in the United States in February 2020, and for use in the European Union in April 2020. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
- Bempedoinsäure ist ein Arzneistoff, der zur Senkung des LDL-Cholesterins bei Erwachsenen mit bestimmten Fettstoffwechselstörung eingesetzt wird. Als Inhibitor der Adenosintriphosphat-Citrat-Lyase (ACL) senkt Bempedoinsäure das LDL-Cholesterin durch Hemmung der Cholesterinsynthese. (de)
- L'acide bempédoïque est une molécule inhibitrice de l'ATP citrate lyase utilisé dans le traitement de l'hypercholestérolémie. (fr)
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- 16442 (xsd:nonNegativeInteger)
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- HYHMLYSLQUKXKP-UHFFFAOYSA-N (en)
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- Bempedoinsäure ist ein Arzneistoff, der zur Senkung des LDL-Cholesterins bei Erwachsenen mit bestimmten Fettstoffwechselstörung eingesetzt wird. Als Inhibitor der Adenosintriphosphat-Citrat-Lyase (ACL) senkt Bempedoinsäure das LDL-Cholesterin durch Hemmung der Cholesterinsynthese. (de)
- L'acide bempédoïque est une molécule inhibitrice de l'ATP citrate lyase utilisé dans le traitement de l'hypercholestérolémie. (fr)
- L'àcid bempedoic, comercialitzat com a Nexletol o Nustendi, és un fàrmac per al tractament de l'hipercolesterolèmia (nivells de colesterol de sang elevats). Els efectes secundaris més comuns inclouen hiperuricèmia (nivells elevats d'àcid úric en sang), dolor a les extremitats, i anèmia (baix recompte d'eritròcits). (ca)
- Bempedoic acid, sold under the brand name Nexletol among others, is a medication for the treatment of hypercholesterolemia (high blood cholesterol levels). The most common side effects include hyperuricemia (high blood levels of uric acid), pain in arms or legs, and anemia (low red blood cell counts). Bempedoic acid blocks an enzyme in the liver called adenosine triphosphate-citrate lyase, which is involved in making cholesterol. (en)
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- Bempedoic acid (en)
- Àcid bempedoic (ca)
- Bempedoinsäure (de)
- Acide bempédoïque (fr)
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