About: Bcl-xL

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B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts as an anti-apoptotic protein by preventing the release of mitochondrial contents such as cytochrome c, which leads to caspase activation and ultimately, programmed cell death.

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  • B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts as an anti-apoptotic protein by preventing the release of mitochondrial contents such as cytochrome c, which leads to caspase activation and ultimately, programmed cell death. (en)
  • Bcl-xL（B-cell lymphoma-extra large）は、遺伝子にコードされる、ミトコンドリアの膜貫通分子である。Bcl-2ファミリーのメンバーであり、シトクロムcなどミトコンドリアの内容物の放出を防ぐことで抗アポトーシスタンパク質として作用する。シトクロムcの放出はカスパーゼの活性化、そして最終的にはプログラム細胞死を引き起こす。 (ja)
  • Bcl-xL è una molecola transmembrana antiapoptotica presente nei mitocondri che regola in modo coordinato l'apoptosi, la fine del ciclo cellulare e l'entrata nel ciclo cellulare, determinando la morte programmata della cellula. (it)
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  • B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts as an anti-apoptotic protein by preventing the release of mitochondrial contents such as cytochrome c, which leads to caspase activation and ultimately, programmed cell death. (en)
  • Bcl-xL（B-cell lymphoma-extra large）は、遺伝子にコードされる、ミトコンドリアの膜貫通分子である。Bcl-2ファミリーのメンバーであり、シトクロムcなどミトコンドリアの内容物の放出を防ぐことで抗アポトーシスタンパク質として作用する。シトクロムcの放出はカスパーゼの活性化、そして最終的にはプログラム細胞死を引き起こす。 (ja)
  • Bcl-xL è una molecola transmembrana antiapoptotica presente nei mitocondri che regola in modo coordinato l'apoptosi, la fine del ciclo cellulare e l'entrata nel ciclo cellulare, determinando la morte programmata della cellula. (it)
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  • Bcl-xL (en)
  • Bcl-xL (it)
  • Bcl-xL (ja)
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