About: Amivantamab

An Entity of Type: monoclonal antibody, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Amivantamab, sold under the brand name Rybrevant, is a bispecific monoclonal antibody used to treat non-small cell lung cancer. The most common side effects include rash, infusion-related reactions, skin infections around the fingernails or toenails, muscle and joint pain, shortness of breath, nausea, fatigue, swelling in the lower legs or hands or face, sores in the mouth, cough, constipation, vomiting and changes in certain blood tests. Amivantamab was approved for medical use in the United States in May 2021, and in the European Union in December 2021.

Property Value
dbo:abstract
  • Amivantamab, sold under the brand name Rybrevant, is a bispecific monoclonal antibody used to treat non-small cell lung cancer. The most common side effects include rash, infusion-related reactions, skin infections around the fingernails or toenails, muscle and joint pain, shortness of breath, nausea, fatigue, swelling in the lower legs or hands or face, sores in the mouth, cough, constipation, vomiting and changes in certain blood tests. Amivantamab is a bispecific epidermal growth factor (EGF) receptor-directed and mesenchymal–epithelial transition (MET) receptor-directed antibody. It is the first treatment for adults with non-small cell lung cancer whose tumors have specific types of genetic mutations: epidermal growth factor receptor (EGFR) exon 20 insertion mutations. Amivantamab was approved for medical use in the United States in May 2021, and in the European Union in December 2021. (en)
  • Amivantamab ist ein monoklonaler Antikörper, der als Arzneistoff zur Behandlung bestimmter Formen des nicht-kleinzelligen Lungenkrebses (NSCLC) eingesetzt wird. Für dieses Anwendungsgebiet erhielt er in den USA im Mai 2021, in der EU im Dezember 2021, unter dem Namen Rybrevant (Janssen Biotech) die Zulassung. (de)
  • Амивантамаб — лекарственный препарат, противоопухолевое моноклональное антитело для лечения рака легких. Одобрен для применения: США (2021). (ru)
dbo:alternativeName
  • Rybrevant (en)
dbo:casNumber
  • 2171511-58-1
dbo:class
dbo:drugbank
  • DB16695
dbo:fdaUniiCode
  • 0JSR7Z0NB6
dbo:kegg
  • D11894
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 67738863 (xsd:integer)
dbo:wikiPageLength
  • 16830 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1119142111 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • L01 (en)
dbp:atcSuffix
  • FX18 (en)
dbp:c
  • 6472 (xsd:integer)
dbp:casNumber
  • 2171511 (xsd:integer)
dbp:class
dbp:dailymedid
  • Amivantamab (en)
dbp:drugbank
  • DB16695 (en)
dbp:h
  • 10014 (xsd:integer)
dbp:kegg
  • D11894 (en)
dbp:legalCa
  • Rx-only (en)
dbp:legalCaComment
  • / Schedule D (en)
dbp:legalEu
  • Rx-only (en)
dbp:legalUs
  • Rx-only (en)
dbp:mabType
  • mab (en)
dbp:n
  • 1730 (xsd:integer)
dbp:o
  • 2023 (xsd:integer)
dbp:routesOfAdministration
dbp:s
  • 46 (xsd:integer)
dbp:source
  • u (en)
dbp:synonyms
  • JNJ-61186372, amivantamab-vmjw (en)
dbp:target
  • Epidermal growth factor receptor and Mesenchymal–epithelial transition (en)
dbp:tradename
  • Rybrevant (en)
dbp:type
  • mab (en)
dbp:unii
  • 0 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Amivantamab ist ein monoklonaler Antikörper, der als Arzneistoff zur Behandlung bestimmter Formen des nicht-kleinzelligen Lungenkrebses (NSCLC) eingesetzt wird. Für dieses Anwendungsgebiet erhielt er in den USA im Mai 2021, in der EU im Dezember 2021, unter dem Namen Rybrevant (Janssen Biotech) die Zulassung. (de)
  • Амивантамаб — лекарственный препарат, противоопухолевое моноклональное антитело для лечения рака легких. Одобрен для применения: США (2021). (ru)
  • Amivantamab, sold under the brand name Rybrevant, is a bispecific monoclonal antibody used to treat non-small cell lung cancer. The most common side effects include rash, infusion-related reactions, skin infections around the fingernails or toenails, muscle and joint pain, shortness of breath, nausea, fatigue, swelling in the lower legs or hands or face, sores in the mouth, cough, constipation, vomiting and changes in certain blood tests. Amivantamab was approved for medical use in the United States in May 2021, and in the European Union in December 2021. (en)
rdfs:label
  • Amivantamab (en)
  • Amivantamab (de)
  • Амивантамаб (ru)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:product of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License