About: AP-1 transcription factor

An Entity of Type: Biomolecule, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

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dbo:description
  • instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560) (en)
dbo:symbol
  • AP-1
  • Leuzip_Jun
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dbo:wikiPageExternalLink
dbo:wikiPageWikiLink
dbp:activatedBy
  • PDTC, IE1, JNK, RIP2, TPA, PDCD4, KSHV, MAPK, Serralysin, PRL, K15, Alpha lipoic acid, Phorbol esters, Cytokine, (en)
dbp:activates
  • cAMP, IL-2, CREB, WEE1, OPN, RD, MMP, calpain-2, G1-Cyclin–dependent Kinases, BMP-4, H1 receptor, cyclin D1, GC-A, TGF-b, NOTCH4, Blimp-1, FasL, TNF-a, c-jun, Bcl-xl, ECs, miR-21, Cox-2, PtdInsP2, tissue factor, HMG-I/Y, PTH, TPA-response element, Gap-43 protein, hMT IIA, TGF-B1, IL-8, IL-4, IL-5, GM-CSF, hGSTP1, Egr-1, Fibronectin, (en)
dbp:align
  • right (en)
dbp:alt
  • Side view (en)
  • Helical wheel (en)
dbp:captionAlign
  • center (en)
dbp:footer
  • C-JUN homodimer Left: The helical wheel projection of c-jun homodimer. When viewed down the axis, the alpha helices have a ~7 amino acid repeating leucine at position a. Two helices may be aligned so that repeating hydrophobic side chains form an interacting surface which facilitates dimerization. Dashed lines indicate potential electrostatic bridges. Right: Side view of c-jun homodimer. Residues on position a and d in helical wheel diagram are shown. Leucines are colored in blue, and other hydrophobic residues are colored in yellow. (en)
dbp:headerAlign
  • center (en)
dbp:height
  • 933 (xsd:integer)
  • 1627 (xsd:integer)
dbp:image
  • UM chem505 1JUN side view.png (en)
  • UM chem505 group 7 1JUN helical wheel.jpg (en)
dbp:inhibitedBy
  • MIF, BATF Ergothioneine (en)
dbp:inhibits
  • PAI-1, Collagen, HNF-1, Osteocalcin, (en)
dbp:interpro
  • IPR000837 (en)
  • IPR002112 (en)
dbp:name
  • AP-1 Proteins (en)
  • Transcription factor Jun (en)
dbp:symbol
  • AP-1 (en)
  • Leuzip_Jun (en)
dbp:totalWidth
  • 400 (xsd:integer)
dbp:width
  • 850 (xsd:integer)
  • 868 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:label
  • AP-1 transcription factor (en)
  • AP-1 (de)
  • Factor de transcripción AP-1 (es)
  • Facteur de transcription AP-1 (fr)
  • AP-1 (in)
  • AP-1 (ja)
  • AP-1 (pl)
  • AP-1 (транскрипционный фактор) (ru)
  • AP-1转录因子 (zh)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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