About: AFDX-384

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes. It is used mainly for mapping the distribution of M2 and M4 muscarinic receptors in the brain, and studying their involvement in the development and treatment of dementia and schizophrenia.

Property	Value
dbo:abstract	AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes. It is used mainly for mapping the distribution of M2 and M4 muscarinic receptors in the brain, and studying their involvement in the development and treatment of dementia and schizophrenia. (en)
dbo:casNumber	118290-27-0
dbo:chEBI	73338
dbo:pubchem	119357
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dbo:wikiPageWikiLink	dbr:Schizophrenia dbr:Dementia dbc:Piperidines dbc:Ureas dbr:Muscarinic_acetylcholine_receptor dbr:Muscarinic_acetylcholine_receptor_M2 dbr:Muscarinic_acetylcholine_receptor_M4 dbc:Muscarinic_antagonists dbc:Benzodiazepines dbc:Pyridodiazepines dbr:Pirenzepine dbr:Antagonist_(pharmacology)
dbp:c	27 (xsd:integer)
dbp:casNumber	118290 (xsd:integer)
dbp:chebi	73338 (xsd:integer)
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dbp:h	38 (xsd:integer)
dbp:iupacName	N--6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide (en)
dbp:n	6 (xsd:integer)
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dbp:pubchem	119357 (xsd:integer)
dbp:smiles	O=C1Nc2cccnc2NCNCCN3CCCCC3CNCCC (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	MZDYABXXPZNUCT-OAQYLSRUSA-N (en)
dbp:verifiedfields	changed (en)
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dcterms:subject	dbc:Piperidines dbc:Ureas dbc:Muscarinic_antagonists dbc:Benzodiazepines dbc:Pyridodiazepines
gold:hypernym	dbr:Drug
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rdfs:comment	AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes. It is used mainly for mapping the distribution of M2 and M4 muscarinic receptors in the brain, and studying their involvement in the development and treatment of dementia and schizophrenia. (en)
rdfs:label	AFDX-384 (en)
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is foaf:primaryTopic of	wikipedia-en:AFDX-384