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The 2021–22 St. Louis Blues season was the 55th season for the National Hockey League franchise that was established in 1967. On April 16, 2022, the Blues clinched a playoff spot after a 6–5 overtime win against the Minnesota Wild. The Blues set a franchise record with a 16-game point scoring streak from April 1-24. The Blues upset the Minnesota Wild in six games in the First Round, but lost to the Stanley Cup-winning Colorado Avalanche in six games in the Second Round.