The 2016 Motul Sepang 12 Hours was the seventeenth Sepang 12 Hours race held on Sepang International Circuit on 10 December 2016. The race was contested with GT3-spec cars, , GT4 (Supersport)-spec cars, MARC cars and touring cars. This was the second Sepang 12 Hours race organized by the Stéphane Ratel Organisation (SRO). The race was also the third and final round of the inaugural Intercontinental GT Challenge.