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- 1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective antagonist at the 5HT7 serotonin receptor. It was discovered as an active metabolite of the synthetic 5-HT7 agonists LP-12 and LP-211, and unexpectedly turned out to be a potent antagonist with selectivity approaching that of the parent molecules, despite its much simpler structure. (en)
- 1-(2-联苯基)哌嗪是一种有机化合物，化学式为C16H18N2。它可由1-叔丁氧羰基-4-(2-溴苯基)哌嗪和苯硼酸在四(三苯基膦)钯催化下反应制得，或由2-氨基联苯和二(氯乙基)胺盐酸盐在碳酸钾和碘化钾存在下反应得到。它和N-苄基-6-溴己酰胺在碳酸钾存在下于乙腈中回流反应，可以得到N-苄基-(4-联苯-2-基)哌嗪己酰胺。 (zh)
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- 2595 (xsd:nonNegativeInteger)
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- C3CNCCN3c1ccccc1-c2ccccc2 (en)
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- RKRVRTJVCWZOQS-UHFFFAOYSA-N (en)
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- 1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective antagonist at the 5HT7 serotonin receptor. It was discovered as an active metabolite of the synthetic 5-HT7 agonists LP-12 and LP-211, and unexpectedly turned out to be a potent antagonist with selectivity approaching that of the parent molecules, despite its much simpler structure. (en)
- 1-(2-联苯基)哌嗪是一种有机化合物，化学式为C16H18N2。它可由1-叔丁氧羰基-4-(2-溴苯基)哌嗪和苯硼酸在四(三苯基膦)钯催化下反应制得，或由2-氨基联苯和二(氯乙基)胺盐酸盐在碳酸钾和碘化钾存在下反应得到。它和N-苄基-6-溴己酰胺在碳酸钾存在下于乙腈中回流反应，可以得到N-苄基-(4-联苯-2-基)哌嗪己酰胺。 (zh)
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- 1-(2-Diphenyl)piperazine (en)
- 1-(2-联苯基)哌嗪 (zh)
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