About: Phosphoglycerate mutase

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Phosphoglycerate mutase (PGM) is any enzyme that catalyzes step 8 of glycolysis - the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG) through a 2,3-bisphosphoglycerate intermediate. These enzymes are categorized into the two distinct classes of either cofactor-dependent (dPGM) or cofactor-independent (iPGM). The dPGM enzyme (EC 5.4.2.11) is composed of approximately 250 amino acids and is found in all vertebrates as well as in some invertebrates, fungi, and bacteria. The iPGM (EC 5.4.2.12) class is found in all plants and algae as well as in some invertebrate, fungi, and Gram-positive bacteria. This class of PGM enzyme shares the same superfamily as alkaline phosphatase.

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  • فوسفوغلوكوموتاز (بالإنجليزية: phosphoglycerate mutase)‏، تختصر PGM، أحد الإنزيمات التي لها دور في عملية تحلل السكر glycolysis في الخلية.وظيقته هي في الخطوة الثامنة في العملية حيث ينقل مجموعة الفوسفات من الذرة الثالثة إلى الذرة الثانية في مركب 3PGphosphoglycerate ليتحول إلى 2-phosphoglycerate 2PG من خلال إنزيم 2,3-bisphosphoglycerate كوسط للتفاعل. (ar)
  • Phosphoglyceratmutasen (PGAM) sind Enzyme, die die Umlagerung der Phosphatgruppe in Phosphoglycerat von 2- auf 3-Position und umgekehrt katalysieren. Diese Reaktion ist ein Teilschritt in der Glycolyse, der Verwertung von Kohlenhydraten im Stoffwechsel aller Lebewesen, die in jeder Zelle stattfindet. Mit den Säugetieren haben sich durch Kopie zusätzliche Allele des PGAM1-Gens gebildet, die PGAM2, PGAM4 und PGAM5 genannt werden. PGAM2 wird nur in den Muskeln produziert. Mutationen am PGAM2-Gen führen zu einer Form der Muskeldystrophie. (de)
  • La fosfoglicerato mutasa (PGAM) (EC 5.4.2.1) es una enzima isomerasa que cataliza la octava etapa de la glicólisis. Cataliza la transferencia interna de un grupo fosfato desde el carbono C-3 al carbono C-2 que resulta en la conversión de 3-fosfoglicerato a 2-fosfoglicerato a través del compuesto intermedio 2,3-bisfosfoglicerato. La reacción implica a dos grupos fosfato diferentes, es decir el grupo fosfato final del 2-fosfoglicerato no es el mismo que el grupo fosfato inicial del 3-fosfoglicerato. (es)
  • Phosphoglycerate mutase (PGM) is any enzyme that catalyzes step 8 of glycolysis - the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG) through a 2,3-bisphosphoglycerate intermediate. These enzymes are categorized into the two distinct classes of either cofactor-dependent (dPGM) or cofactor-independent (iPGM). The dPGM enzyme (EC 5.4.2.11) is composed of approximately 250 amino acids and is found in all vertebrates as well as in some invertebrates, fungi, and bacteria. The iPGM (EC 5.4.2.12) class is found in all plants and algae as well as in some invertebrate, fungi, and Gram-positive bacteria. This class of PGM enzyme shares the same superfamily as alkaline phosphatase. (en)
  • La phosphoglycérate mutase (PGM) est une isomérase qui catalyse la réaction : 3-phosphoglycérate 2-phosphoglycérate. Cette enzyme intervient à la 8e étape de la glycolyse en catalysant le transfert d'un groupe phosphate de l'atome de carbone C-3 vers l'atome C-2 d'une molécule de 3-phospho-D-glycérate (3PG) pour la convertir en 2-phospho-D-glycérate (2PG). Phosphoglycérate mutase (fr)
  • 포스포글리세르산 뮤테이스(영어: phosphoglycerate mutase, PGM) (EC 5.4.2.1)는 해당과정의 8번째 단계를 촉매하는 효소이다. 포스포글리세르산 뮤테이스는 포스포글리세르산의 3번 탄소의 인산기를 2번 탄소로 내부 전달을 촉매하여 3-포스포글리세르산을 2,3-비스포스포글리세르산을 거쳐 2-포스포글리세르산으로 전환시킨다. 포스포글리세르산 뮤테이스는 보조 인자 의존적 포스포글리세르산 뮤테이스(dPGM)와 보조 인자 비의존적 포스포글리세르산 뮤테이스(iPGM)의 2가지 상이한 부류로 분류된다. 보조 인자 의존적 포스포글리세르산 뮤테이스(dPGM) (EC 5.4.2.11)는 약 250개의 아미노산으로 구성되어 있으며, 모든 척추동물과 일부 무척추동물, 균류, 세균에서 발견된다. 보조 인자 비의존적 포스포글리세르산 뮤테이스(iPGM) (EC 5.4.2.12)는 모든 식물과 조류 뿐만 아니라 일부 무척추동물, 균류 및 그람 양성 세균에서도 발견된다. 이러한 부류의 포스포글리세르산 뮤테이스는 알칼리성 인산가수분해효소와 동일한 슈퍼패밀리를 공유한다. (ko)
  • Il fosfoglicerato mutasi (PGM) è un enzima che catalizza l'ottava reazione della glicolisi. Catalizza il trasferimento interno di un gruppo fosfato da C-3 a C-2 come frutto della conversione 3-fosfoglicerato (3PG) a 2-fosfoglicerato (2PG) attraverso uno stadio intermedio a 2,3-bifosfoglicerato. Nella reazione la fosfoglicerato mutasi sfrutta la presenza di una istidina fosforilata, nel sito attivo dell'enzima, come donatorice di un gruppo fosforilico. Questo viene donato al C2 del 3 fosfoglicerato formando l'intermedio 2,3-bisfosfoglicerato; a questo punto l'enzima prende il gruppo fosforilico in posizione 3 producendo il prodotto finale. Questo enzima è classificato in due diverse classi: cofattore-dipendente (dPGM) e cofattore-indipendente (iPGM). L'enzima dPGM (EC 5.4.2.11) è costituito da circa 250 aminoacidi ed è presente in tutti i vertebrati e in alcuni invertebrati, come funghi e batteri. L'iPGM (EC 5.4.2.12) si trova in tutte le piante e alghe e in alcuni invertebrati, come funghi e batteri gram-positivi. La classe di enzima PGM condivide la stessa superfamiglia fosfatasi alcalina. (it)
  • Fosfogliceromutaza (EC 5.4.2.1) – enzym z klasy izomeraz. Bierze udział w glikolizie, przeprowadzając ósmą reakcję. Przekształca 3-fosfoglicerynian do , na drodze transferu grupy fosforanowej z pozycji C-3 na C-2. (pl)
  • Фосфоглицератмутаза (англ. Phosphoglycerate mutase, PGM), также фосфоглицеромутаза — фермент, катализирующий реакцию внутреннего переноса фосфатной группы с C-3 на C-2, превращающей 3-фосфоглицерат в 2-фосфоглицерат (стадия 8 гликолиза). (ru)
  • 磷酸甘油酸变位酶（英語：Phosphoglycerate mutase，PGM，EC 5.4.2.11）是一种催化3-磷酸甘油酸（3PG）转变为2-磷酸甘油酸（2PG）的酶，这个反应是糖酵解途径的第八步，其中间产物是2,3-二磷酸甘油酸（2,3BPG）反应式如下： 3PG + P-Enzyme → 2,3BPG + Enzyme → 2PG + P-Enzyme ΔG°′=+1.1kcal/mol * 3PG * 2,3BPG * 2PG (zh)
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  • فوسفوغلوكوموتاز (بالإنجليزية: phosphoglycerate mutase)‏، تختصر PGM، أحد الإنزيمات التي لها دور في عملية تحلل السكر glycolysis في الخلية.وظيقته هي في الخطوة الثامنة في العملية حيث ينقل مجموعة الفوسفات من الذرة الثالثة إلى الذرة الثانية في مركب 3PGphosphoglycerate ليتحول إلى 2-phosphoglycerate 2PG من خلال إنزيم 2,3-bisphosphoglycerate كوسط للتفاعل. (ar)
  • Phosphoglyceratmutasen (PGAM) sind Enzyme, die die Umlagerung der Phosphatgruppe in Phosphoglycerat von 2- auf 3-Position und umgekehrt katalysieren. Diese Reaktion ist ein Teilschritt in der Glycolyse, der Verwertung von Kohlenhydraten im Stoffwechsel aller Lebewesen, die in jeder Zelle stattfindet. Mit den Säugetieren haben sich durch Kopie zusätzliche Allele des PGAM1-Gens gebildet, die PGAM2, PGAM4 und PGAM5 genannt werden. PGAM2 wird nur in den Muskeln produziert. Mutationen am PGAM2-Gen führen zu einer Form der Muskeldystrophie. (de)
  • La fosfoglicerato mutasa (PGAM) (EC 5.4.2.1) es una enzima isomerasa que cataliza la octava etapa de la glicólisis. Cataliza la transferencia interna de un grupo fosfato desde el carbono C-3 al carbono C-2 que resulta en la conversión de 3-fosfoglicerato a 2-fosfoglicerato a través del compuesto intermedio 2,3-bisfosfoglicerato. La reacción implica a dos grupos fosfato diferentes, es decir el grupo fosfato final del 2-fosfoglicerato no es el mismo que el grupo fosfato inicial del 3-fosfoglicerato. (es)
  • Phosphoglycerate mutase (PGM) is any enzyme that catalyzes step 8 of glycolysis - the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG) through a 2,3-bisphosphoglycerate intermediate. These enzymes are categorized into the two distinct classes of either cofactor-dependent (dPGM) or cofactor-independent (iPGM). The dPGM enzyme (EC 5.4.2.11) is composed of approximately 250 amino acids and is found in all vertebrates as well as in some invertebrates, fungi, and bacteria. The iPGM (EC 5.4.2.12) class is found in all plants and algae as well as in some invertebrate, fungi, and Gram-positive bacteria. This class of PGM enzyme shares the same superfamily as alkaline phosphatase. (en)
  • La phosphoglycérate mutase (PGM) est une isomérase qui catalyse la réaction : 3-phosphoglycérate 2-phosphoglycérate. Cette enzyme intervient à la 8e étape de la glycolyse en catalysant le transfert d'un groupe phosphate de l'atome de carbone C-3 vers l'atome C-2 d'une molécule de 3-phospho-D-glycérate (3PG) pour la convertir en 2-phospho-D-glycérate (2PG). Phosphoglycérate mutase (fr)
  • 포스포글리세르산 뮤테이스(영어: phosphoglycerate mutase, PGM) (EC 5.4.2.1)는 해당과정의 8번째 단계를 촉매하는 효소이다. 포스포글리세르산 뮤테이스는 포스포글리세르산의 3번 탄소의 인산기를 2번 탄소로 내부 전달을 촉매하여 3-포스포글리세르산을 2,3-비스포스포글리세르산을 거쳐 2-포스포글리세르산으로 전환시킨다. 포스포글리세르산 뮤테이스는 보조 인자 의존적 포스포글리세르산 뮤테이스(dPGM)와 보조 인자 비의존적 포스포글리세르산 뮤테이스(iPGM)의 2가지 상이한 부류로 분류된다. 보조 인자 의존적 포스포글리세르산 뮤테이스(dPGM) (EC 5.4.2.11)는 약 250개의 아미노산으로 구성되어 있으며, 모든 척추동물과 일부 무척추동물, 균류, 세균에서 발견된다. 보조 인자 비의존적 포스포글리세르산 뮤테이스(iPGM) (EC 5.4.2.12)는 모든 식물과 조류 뿐만 아니라 일부 무척추동물, 균류 및 그람 양성 세균에서도 발견된다. 이러한 부류의 포스포글리세르산 뮤테이스는 알칼리성 인산가수분해효소와 동일한 슈퍼패밀리를 공유한다. (ko)
  • Fosfogliceromutaza (EC 5.4.2.1) – enzym z klasy izomeraz. Bierze udział w glikolizie, przeprowadzając ósmą reakcję. Przekształca 3-fosfoglicerynian do , na drodze transferu grupy fosforanowej z pozycji C-3 na C-2. (pl)
  • Фосфоглицератмутаза (англ. Phosphoglycerate mutase, PGM), также фосфоглицеромутаза — фермент, катализирующий реакцию внутреннего переноса фосфатной группы с C-3 на C-2, превращающей 3-фосфоглицерат в 2-фосфоглицерат (стадия 8 гликолиза). (ru)
  • 磷酸甘油酸变位酶（英語：Phosphoglycerate mutase，PGM，EC 5.4.2.11）是一种催化3-磷酸甘油酸（3PG）转变为2-磷酸甘油酸（2PG）的酶，这个反应是糖酵解途径的第八步，其中间产物是2,3-二磷酸甘油酸（2,3BPG）反应式如下： 3PG + P-Enzyme → 2,3BPG + Enzyme → 2PG + P-Enzyme ΔG°′=+1.1kcal/mol * 3PG * 2,3BPG * 2PG (zh)
  • Il fosfoglicerato mutasi (PGM) è un enzima che catalizza l'ottava reazione della glicolisi. Catalizza il trasferimento interno di un gruppo fosfato da C-3 a C-2 come frutto della conversione 3-fosfoglicerato (3PG) a 2-fosfoglicerato (2PG) attraverso uno stadio intermedio a 2,3-bifosfoglicerato. Nella reazione la fosfoglicerato mutasi sfrutta la presenza di una istidina fosforilata, nel sito attivo dell'enzima, come donatorice di un gruppo fosforilico. Questo viene donato al C2 del 3 fosfoglicerato formando l'intermedio 2,3-bisfosfoglicerato; a questo punto l'enzima prende il gruppo fosforilico in posizione 3 producendo il prodotto finale. (it)
rdfs:label
  • فوسفوغليسيرات موتاز (ar)
  • Phosphoglyceratmutase (de)
  • Fosfoglicerato mutasa (es)
  • Phosphoglycérate mutase (fr)
  • Fosfoglicerato mutasi (it)
  • 포스포글리세레이트 뮤테이스 (ko)
  • Phosphoglycerate mutase (en)
  • Fosfogliceromutaza (pl)
  • Фосфоглицератмутаза (ru)
  • 磷酸甘油酸变位酶 (zh)
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  • phosphoglycerate mutase 1 (brain) (en)
  • phosphoglycerate mutase 2 (muscle) (en)
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