dbo:abstract
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- Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. First, they have been described as members of the CREB/ATF family, whereas it turned out later that some of them might be more similar to AP-1-like factors such as c-Jun or c-Fos. In general, ATFs are known to respond to extracellular signals and this suggests an important role that they have in maintaining homeostasis. Some of these ATFs, such as ATF3, ATF4, and ATF6 are known to play a role in stress responses. Another example of ATFs function would be ATFx that can suppress apoptosis. Genes include ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, ATF7, ATFx. (en)
- En biología molecular, se denomina factor de transcripción activador (o también ATF) a una clase de factores de transcripción AP-1 diméricos. Se han descrito diversos factores de transcripción activadores, pudiéndose identificar los siguientes:
* ATF1
* ATF2
* ATF3
* ATF4
* ATF5
* ATF6
* ATF7 (es)
- Les ATF (pour « Activating transcription factor ») sont une famille de protéines jouant un rôle de facteur de transcription et comportant un domaine bZIP. Elle comporte plusieurs membres : , , ATF3, ATF4, , ATF6, et .
* Portail de la biologie cellulaire et moléculaire (fr)
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rdfs:comment
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- En biología molecular, se denomina factor de transcripción activador (o también ATF) a una clase de factores de transcripción AP-1 diméricos. Se han descrito diversos factores de transcripción activadores, pudiéndose identificar los siguientes:
* ATF1
* ATF2
* ATF3
* ATF4
* ATF5
* ATF6
* ATF7 (es)
- Les ATF (pour « Activating transcription factor ») sont une famille de protéines jouant un rôle de facteur de transcription et comportant un domaine bZIP. Elle comporte plusieurs membres : , , ATF3, ATF4, , ATF6, et .
* Portail de la biologie cellulaire et moléculaire (fr)
- Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. First, they have been described as members of the CREB/ATF family, whereas it turned out later that some of them might be more similar to AP-1-like factors such as c-Jun or c-Fos. In general, ATFs are known to respond to extracellular signals and this suggests an important role that they have in maintaining homeostasis. Some of these ATFs, such as ATF3, ATF4, and ATF6 are known to play a role in stress responses. Another example of ATFs function would be ATFx that can suppress apoptosis. (en)
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- Activating transcription factor (en)
- Factor de transcripción activador (es)
- ATF (protéine) (fr)
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