About: White Collar-2

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The white collar--2 (wc-2) gene in Neurospora crassa encodes the protein White Collar-2 (WC-2). WC-2 is a GATA transcription factor necessary for blue light photoreception and for regulating circadian rhythms in Neurospora. In both contexts, WC-2 binds to its non-redundant counterpart White Collar-1 (WC-1) through PAS domains to form the White Collar Complex (WCC), an active transcription factor.

Attributes	Values
rdfs:label	White Collar-2 (en)
rdfs:comment	The white collar--2 (wc-2) gene in Neurospora crassa encodes the protein White Collar-2 (WC-2). WC-2 is a GATA transcription factor necessary for blue light photoreception and for regulating circadian rhythms in Neurospora. In both contexts, WC-2 binds to its non-redundant counterpart White Collar-1 (WC-1) through PAS domains to form the White Collar Complex (WCC), an active transcription factor. (en)
dcterms:subject	Transcription factors Fungal proteins
Wikipage page ID	53761758 (xsd:integer)
Wikipage revision ID	1118748674 (xsd:integer)
Link from a Wikipage to another Wikipage	Mouse Hydrogen bond Light-oxygen-voltage-sensing domain Null allele Essential gene Gene knockout Gene redundancy Circadian rhythm Colin Pittendrigh Fungus Conidiation Conidium Photoreceptor protein GATA transcription factor Alpha helix Amino acid Drosophila Flavin adenine dinucleotide PAS domain Kinase Transcription factor Promoter (genetics) ARNTL Transcription factors Zinc finger White Collar 1 Fungal proteins CLOCK Frequency (gene) Neurospora Carotenoid Neurospora crassa Mycelium White Collar-1 Heterodimer Heterodimerize Negative feedback loop
Link from a Wikipage to an external page	https://geiselmed.dartmouth.edu/dunlaploros/research/
sameAs	White Collar-2 White Collar-2
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Short_description
has abstract	The white collar--2 (wc-2) gene in Neurospora crassa encodes the protein White Collar-2 (WC-2). WC-2 is a GATA transcription factor necessary for blue light photoreception and for regulating circadian rhythms in Neurospora. In both contexts, WC-2 binds to its non-redundant counterpart White Collar-1 (WC-1) through PAS domains to form the White Collar Complex (WCC), an active transcription factor. The WCC has two major and distinct roles in the cell. In the light, the WCC acts as a photoreceptor to mediate acute regulation of light-induced genes involved in various physiological processes such as carotenoid (type of pigment) biosynthesis and conidiation. In a separate and distinct role in the dark, WCC acts as the positive element in the autoregulatory transcription-translation negative feedback loop that controls circadian rhythmic behaviors in Neurospora. In this context, WCC regulates expression of the Frequency (FRQ) gene, a light-induced clock protein. (en)
prov:wasDerivedFrom	wikipedia-en:White_Collar-2?oldid=1118748674&ns=0
page length (characters) of wiki page	14608 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:White_Collar-2
is Link from a Wikipage to another Wikipage of	Dual circadian oscillator model Jay Dunlap Transcription translation feedback loop White Collar-1 WC2
is foaf:primaryTopic of	wikipedia-en:White_Collar-2

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