Tangascootack Creek (also known as Scootack or Tangascootac Creek) is a tributary of the West Branch Susquehanna River in Clinton County, Pennsylvania in the United States. Tangascootack Creek stretches for 11.4 miles (18.3 km) through Bald Eagle, Beech Creek and Colebrook Townships. Its watershed covers 36.5 square miles. Among its tributaries are North Fork Tangascootack Creek and Muddy Run, and there is also a swamp called Bear Swamp near the headwaters. Coal mining, including strip mining, was common in the watershed throughout the 1800s and 1900s. The creek experiences acid mine drainage, much of which comes from Muddy Run.