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Relacorilant (developmental code name CORT-125134) is an antiglucocorticoid which is under development by Corcept Therapeutics for the treatment of Cushing's syndrome. It is also under development for the treatment of solid tumors and alcoholism. The drug is a nonsteroidal compound and acts as an antagonist of the glucocorticoid receptor. As of December 2017, it is in phase II clinical trials for Cushing's syndrome and phase I/II clinical studies for solid tumors, while the clinical phase for alcoholism is unknown.

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  • Relacorilant (en)
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  • Relacorilant (developmental code name CORT-125134) is an antiglucocorticoid which is under development by Corcept Therapeutics for the treatment of Cushing's syndrome. It is also under development for the treatment of solid tumors and alcoholism. The drug is a nonsteroidal compound and acts as an antagonist of the glucocorticoid receptor. As of December 2017, it is in phase II clinical trials for Cushing's syndrome and phase I/II clinical studies for solid tumors, while the clinical phase for alcoholism is unknown. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Relacorilant.svg
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IUPAC name
  • [-1--6-sulfonyl-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-4a-yl]-[4-pyridin-2-yl]methanone (en)
KEGG
  • D11336 (en)
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SMILES
  • CN1C=CSN2CCC3=CC4=CC=NN4C6=CC=CF (en)
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  • WANIDIGFXJFFEL-SANMLTNESA-N (en)
synonyms
  • CORT-125134 (en)
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  • Relacorilant (developmental code name CORT-125134) is an antiglucocorticoid which is under development by Corcept Therapeutics for the treatment of Cushing's syndrome. It is also under development for the treatment of solid tumors and alcoholism. The drug is a nonsteroidal compound and acts as an antagonist of the glucocorticoid receptor. As of December 2017, it is in phase II clinical trials for Cushing's syndrome and phase I/II clinical studies for solid tumors, while the clinical phase for alcoholism is unknown. (en)
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CAS number
  • 1496510-51-0
FDA UNII code
  • 2158753C7E
KEGG
  • D11336
PubChem
  • 73051463
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