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About: dbr:Glucocorticoid_receptor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit109465459, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:WikicatTranscriptionFactorsyago:Abstraction100002137yago:Act100030358yago:Activity100407535yago:Beginning107290905yago:BodySubstance105263850yago:Cause107326557yago:Chemical114806838yago:Compound114818238yago:Corticosteroid114751417yago:Event100029378yago:Factor107327805yago:Glucocorticoid114752057yago:Happening107283608yago:Hormone105407119yago:LiquidBodySubstance105397468yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:OrganicCompound114727670yago:Origin107323922yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:PsychologicalFeature100023100yago:Relation100031921yago:WikicatGenomeProjectsyago:WikicatGlucocorticoidsyago:Work100575741yago:YagoPermanentlyLocatedEntityHumanGeneproteinyago:Secretion105404728yago:SteroidHormone114745635yago:Substance100019613yago:Thing100002452yago:Undertaking100795720yago:Unit109465459 New Facet based on Instances of this Class

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. Because the receptor gene is expressed in several forms, it has many different (pleiotropic) effects in different parts of the body. In humans, the GR protein is encoded by NR3C1 gene which is located on chromosome 5 (5q31).