Pointe Mouillee State Game Area (/ˈpɔɪnt mwiːˈjeɪ/; point mwee-YAY or moo-LAY) is a state game area in the U.S. state of Michigan. It encompasses 7,483 acres (30.3 km2) of hunting, recreational, and protected wildlife and wetland areas at the mouth of the Huron River at Lake Erie, as well as smaller outlying areas within the Detroit River. Pointe Mouillee State Game Area was established in 1945 and is administered by the Michigan Department of Natural Resources.