The Lucy Walker steamboat disaster was an 1844 steamboat accident caused by the explosion of the boilers of the steamboat Lucy Walker near New Albany, Indiana, on the Ohio River. The explosion occurred on the afternoon of Wednesday, October 23, 1844, when the steamer's three boilers exploded, set the vessel on fire, and sank it. It was one of a number of similar accidents of early 19th-century riverine transportation that led to important federal legislation and safety regulations. The vessel's owner was a Native American; her crew were African-American slaves, and her passengers represented a cross-section of frontier travelers.