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Hypokalemic periodic paralysis (hypoKPP), also known as familial hypokalemic periodic paralysis (FHPP), is a rare, autosomal dominant channelopathy characterized by muscle weakness or paralysis when there is a fall in potassium levels in the blood. In individuals with this mutation, attacks sometimes begin in adolescence and most commonly occur with individual triggers such as rest after strenuous exercise (attacks during exercise are rare), high carbohydrate meals, meals with high sodium content, sudden changes in temperature, and even excitement, noise, flashing lights, cold temperatures and stress. Weakness may be mild and limited to certain muscle groups, or more severe full-body paralysis. During an attack, reflexes may be decreased or absent. Attacks may last for a few hours or persi

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  • شلل نقص بوتاسيوم الدم الدوري (ar)
  • Hypokalemic periodic paralysis (en)
  • Paralysie périodique hypokaliémique (fr)
  • Paralisi periodica ipocaliemica (it)
  • Hipokaliemiczne porażenie okresowe (pl)
  • Paralisia periódica hipocalémica (pt)
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  • شَلَلُ نَقْصِ بُوتاسيوم الدَّمِ الدَّورِيّ (بالإنجليزية: Hypokalemic periodic paralysis)‏ هو نادر، وهو اعتلال القنوات سيادي يؤدي إلى نوبات متكررة من ضًعف العضلات وأحيانًا نقص في مستوى البوتاسيوم في الدم (يرجع السبب بشكل أساسي إلى ). (ar)
  • Paralisia periódica hipocalémica (hipoPP) uma doença hereditária rara caracterizada por episódios de com duração de algumas horas a 24-48 horas e associada a baixos níveis de potássio no sangue. A doença afeta geralmente os quatro membros e resulta em tetraplegia. Estima-se que a doença afete 1 em cada 100 000 pessoas. (pt)
  • Hypokalemic periodic paralysis (hypoKPP), also known as familial hypokalemic periodic paralysis (FHPP), is a rare, autosomal dominant channelopathy characterized by muscle weakness or paralysis when there is a fall in potassium levels in the blood. In individuals with this mutation, attacks sometimes begin in adolescence and most commonly occur with individual triggers such as rest after strenuous exercise (attacks during exercise are rare), high carbohydrate meals, meals with high sodium content, sudden changes in temperature, and even excitement, noise, flashing lights, cold temperatures and stress. Weakness may be mild and limited to certain muscle groups, or more severe full-body paralysis. During an attack, reflexes may be decreased or absent. Attacks may last for a few hours or persi (en)
  • La paralysie périodique hypokaliémique ou maladie de Westphal est une maladie génétique se manifestant sous deux phénotypes différents : la forme paralytique et la forme myopathique associée à une hypokaliémie. Les personnes atteintes de paralysie périodique hypokaliémique ont autant de risque d'hyperthermie maligne que les individus porteurs du gène responsable de cette pathologie. (fr)
  • La paralisi periodica ipocaliemica sigla inglese HypoKPP) è un disturbo miopatico che prevede la presenza di occasionali episodi di debolezza muscolare fluttuante, dovuto a eccessivo consumo di potassio durante le fasi critiche, a causa di disfunzioni dei canali ionici della giunzione neuromuscolare. Si tratta di una canalopatia neuromuscolare. Le cellule assorbono troppo potassio lasciandone poco disponibile nel sangue: a causa di una disfunzione dei canali del sodio o del calcio, i canali del potassio diventano iperattivi consumandone troppo. (it)
  • Okresowy paraliż hipokaliemiczny (lub hipokaliemiczne porażenie okresowe) jest rzadką kanałopatią, charakteryzującą się okresowym niedowładem lub porażeniem występującym wraz ze znacznym spadkiem poziomu potasu we krwi. Objawy choroby mają charakter napadowy i zdarzają się najczęściej w nocy lub rano, przy nagłych zmianach temperatury, lub po spożyciu posiłku z dużą ilością węglowodanów albo sodu. Mogą trwać od kilku do nawet 48 godzin. Niedowład może być łagodny i ograniczony do jednej grupy mięśni, lecz może wystąpić także uogólniony paraliż prowadzący do niewydolności oddechowej i śmierci. (pl)
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  • Hypokalemic periodic paralysis (en)
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  • Hypokalemic periodic paralysis (en)
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