German submarine U-758 was a Type VIIC U-boat built for Nazi Germany's Kriegsmarine for service during World War II. Commissioned on 5 May 1942, she served with the 6th U-boat Flotilla until 1 November as a training boat, and as a front boat until 14 October 1944 mostly under the command of Kapitänleutnant Helmut Manseck before joining the 33rd U-boat Flotilla as a training boat for the remainder of her service in the war.