François Loeser (born August 25, 1958) is a French mathematician. He is Professor of Mathematics at the Pierre-and-Marie-Curie University in Paris. From 2000 to 2010 he was Professor at École Normale Supérieure. Since 2015, he is a senior member of the Institut Universitaire de France. He is a specialist of algebraic geometry and is best known for his work on motivic integration, part of it in collaboration with Jan Denef.