Catherine Spalding, known as Mother Spalding, (December 23, 1793 – March 20, 1858) was an American educator who was a co-founder and longtime mother superior of the Sisters of Charity of Nazareth. She pioneered education, health services and social services for girls and orphans in Louisville and other Kentucky cities. On January 6, 2003, the Louisville Courier-Journal named Spalding as the only woman among sixteen "most influential people in Louisville/Jefferson County history."