Anne Wetzell Armstrong (September 20, 1872 – March 17, 1958) was an American novelist and businesswoman, active primarily in the first half of the 20th century. She is best known for her novel, This Day and Time, an account of life in a rural Appalachian community. She was also a pioneering woman in business management, and was the first woman to lecture before the Harvard School of Business and Dartmouth's Tuck School of Business in the early 1920s.