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Amphinase is a ribonuclease enzyme found in the oocytes of the Northern leopard frog (Rana pipiens). Amphinase is a member of the pancreatic ribonuclease protein superfamily and degrades long RNA substrates. Along with ranpirnase, another leopard frog ribonuclease, amphinase has been studied as a potential cancer therapy due to its unusual mechanism of cytotoxicity tested against tumor cells.

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  • Amphinase (en)
  • Amphinase (fr)
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  • Amphinase is a ribonuclease enzyme found in the oocytes of the Northern leopard frog (Rana pipiens). Amphinase is a member of the pancreatic ribonuclease protein superfamily and degrades long RNA substrates. Along with ranpirnase, another leopard frog ribonuclease, amphinase has been studied as a potential cancer therapy due to its unusual mechanism of cytotoxicity tested against tumor cells. (en)
  • L'amphinase est une ribonucléase présente dans les ovocytes de la grenouille léopard (Rana pipiens). Elle est de la même famille que la ribonucléase pancréatique et clive les molécules d'ARN de grande taille. Avec la ranpirnase, autre ribonucléase des ovocytes de la grenouille léopard, elle a fait l'objet d'études infructueuses afin d'évaluer son potentiel thérapeutique en raison de sa cytotoxicité sélective contre les cellules cancéreuses. (fr)
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  • Amphinase (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/2P7S.png
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  • Crystallographic structure of amphinase. (en)
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  • Rana pipiens (en)
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  • n/a (en)
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  • P85073 (en)
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  • Amphinase is a ribonuclease enzyme found in the oocytes of the Northern leopard frog (Rana pipiens). Amphinase is a member of the pancreatic ribonuclease protein superfamily and degrades long RNA substrates. Along with ranpirnase, another leopard frog ribonuclease, amphinase has been studied as a potential cancer therapy due to its unusual mechanism of cytotoxicity tested against tumor cells. (en)
  • L'amphinase est une ribonucléase présente dans les ovocytes de la grenouille léopard (Rana pipiens). Elle est de la même famille que la ribonucléase pancréatique et clive les molécules d'ARN de grande taille. Avec la ranpirnase, autre ribonucléase des ovocytes de la grenouille léopard, elle a fait l'objet d'études infructueuses afin d'évaluer son potentiel thérapeutique en raison de sa cytotoxicité sélective contre les cellules cancéreuses. (fr)
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