46 West 55th Street (also the Joseph B. and Josephine H. Bissell House) is a commercial building in the Midtown Manhattan neighborhood of New York City. It is along the south side of 55th Street between Fifth Avenue and Sixth Avenue. The five-story building was designed by Thomas Thomas in the Italianate style and was constructed in 1869. It was redesigned in the neoclassical style between 1903 and 1904 by Edward L. Tilton. As redesigned by Tilton, the first floor contains a limestone entrance, while the other floors contain red and black brick with limestone moldings. The first four stories are bowed slightly outward.