The 2022–23 UIC Flames men's basketball team will represent the University of Illinois at Chicago in the 2022–23 NCAA Division I men's basketball season. The Flames, led by third-year head coach Luke Yaklich, will play their home games at Credit Union 1 Arena in Chicago, Illinois as members of the Missouri Valley Conference. The 2022–23 season will be the Flames' first season in the Missouri Valley Conference.