The 2021 Chevrolet Silverado 250 was a NASCAR Camping World Truck Series race that was held on October 2, 2021, at Talladega Superspeedway in Lincoln, Alabama. Contested over 99 laps—extended from 94 laps due to an overtime finish—on the 2.66 mi (4.28 km) asphalt superspeedway, it was the 20th race of the 2021 NASCAR Camping World Truck Series season, the fifth race of the Playoffs, and the second race of the Round of 8. In a wild finish that saw numerous lead changes, Tate Fogleman and John Hunter Nemechek would collide, with Nemechek spinning. Fogleman would then hold off the charging Tyler Hill on the final lap to collect his first career Truck series victory.