The 2015–16 UNLV Runnin' Rebels basketball team represented the University of Nevada, Las Vegas during the 2015–16 NCAA Division I men's basketball season. The Runnin' Rebels were led by fifth year head coach Dave Rice until he was fired on January 10, 2016. They were then led by interim head coach Todd Simon for the remainder of the season. They played their home games at the Thomas & Mack Center in Paradise, Nevada as members of the Mountain West Conference. They finished the season 18–15, 8–10 in Mountain West play to finish in a tie for sixth place. They defeated Air Force to advance to the quarterfinals of the Mountain West tournament where they lost to Fresno State.