The 2006 CIS football season began on September 2, 2006, and concluded with the 42nd Vanier Cup national championship on November 25 at Griffiths Stadium in Saskatoon, Saskatchewan, with the Laval Rouge et Or winning their fourth championship. Twenty-seven universities across Canada competed in CIS football this season, the highest level of amateur play in Canadian football, under the auspices of Canadian Interuniversity Sport (CIS).