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Tirbanibulin, sold under the brand name Klisyri, is a medication for the treatment of actinic keratosis (AKs) on the face or scalp. The most common side effects include local skin reactions, application site pruritus, and application site pain. Tirbanibulin was approved for medical use in the United States in December 2020, and in the European Union in July 2021. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.

AttributesValues
rdf:type
rdfs:label
  • Tirbanibulin (de)
  • Tirbanibulin (en)
rdfs:comment
  • Tirbanibulin, vermarktet unter dem Markennamen Klisyri (Almirall), ist ein Arzneistoff zur Behandlung von aktinischer Keratose im Gesicht oder auf der Kopfhaut. Es wirkt als Mitosehemmer. (de)
  • Tirbanibulin, sold under the brand name Klisyri, is a medication for the treatment of actinic keratosis (AKs) on the face or scalp. The most common side effects include local skin reactions, application site pruritus, and application site pain. Tirbanibulin was approved for medical use in the United States in December 2020, and in the European Union in July 2021. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Tirbanibulin-line.png
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Wikipage page ID
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Link from a Wikipage to another Wikipage
Link from a Wikipage to an external page
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dbp:wikiPageUsesTemplate
thumbnail
ATC suffix
  • BX03 (en)
ATC prefix
  • D06 (en)
c
CAS number
ChEMBL
ChemSpiderID
class
DrugBank
  • DB06137 (en)
H
IUPAC name
  • N-benzyl-2-[5-[4-phenyl]pyridin-2-yl]acetamide (en)
KEGG
  • D11691 (en)
legal US
  • Rx-only (en)
n
O
PubChem
routes of administration
SMILES
  • O=CNCc1ccccc1 (en)
StdInChI
StdInChIKey
  • HUNGUWOZPQBXGX-UHFFFAOYSA-N (en)
synonyms
  • KX2-391 (en)
tradename
  • Klisyri (en)
UNII
width
has abstract
  • Tirbanibulin, vermarktet unter dem Markennamen Klisyri (Almirall), ist ein Arzneistoff zur Behandlung von aktinischer Keratose im Gesicht oder auf der Kopfhaut. Es wirkt als Mitosehemmer. (de)
  • Tirbanibulin, sold under the brand name Klisyri, is a medication for the treatment of actinic keratosis (AKs) on the face or scalp. The most common side effects include local skin reactions, application site pruritus, and application site pain. Tirbanibulin was approved for medical use in the United States in December 2020, and in the European Union in July 2021. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. It functions as a mitotic inhibitor by inhibiting tubulin polymerization and Src kinase signaling can be potentially effective in deferring the development of AKs to squamous cell carcinoma in situ. (en)
DailyMedID
  • Tirbanibulin (en)
legal EU
  • Rx-only (en)
PDB ligand
  • DN0 (en)
prov:wasDerivedFrom
page length (characters) of wiki page
alternative name
  • Klisyri (en)
CAS number
  • 897016-82-9
ChEMBL
  • 571546
DrugBank
  • DB06137
FDA UNII code
  • 4V9848RS5G
KEGG
  • D11691
PubChem
  • 23635314
class
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