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About: dbr:Protein_C     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatPeripheralMembraneProteins, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:Abstraction100002137yago:Arrangement107938773yago:Chemical114806838yago:Compound114818238yago:ConjugatedProtein114731135yago:Gene105436752yago:Glycoprotein114888310yago:Group100031264yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:Ordering108456993yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921yago:WikicatGenesOnChromosome2yago:WikicatGlycoproteinsyago:WikicatHumanProteinsHumanGeneproteinyago:Sequence108459252yago:Series108457976yago:Substance100019613yago:Thing100002452yago:Unit109465459yago:WikicatPeripheralMembraneProteins New Facet based on Instances of this Class

Protein C, also known as autoprothrombin IIA and blood coagulation factor XIX, is a zymogen, that is, an inactive enzyme. The activated form plays an important role in regulating anticoagulation, inflammation, and cell death and maintaining the permeability of blood vessel walls in humans and other animals. Activated protein C (APC) performs these operations primarily by proteolytically inactivating proteins Factor Va and Factor VIIIa. APC is classified as a serine protease since it contains a residue of serine in its active site. In humans, protein C is encoded by the PROC gene, which is found on chromosome 2.