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About: Epelsiban     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatPyridines, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substancePill (pharmacy)yago:Abstraction100002137yago:Base114618253yago:Chemical114806838yago:Compound114818238yago:Hydrocarbon114911057yago:Indene114824906yago:Material114580897yago:Matter100020827yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Pyridine114692510yago:Relation100031921yago:WikicatIndenesdrugyago:Substance100019613yago:WikicatPyridines New Facet based on Instances of this Class

Epelsiban (INN, USAN, code name GSK-557,296-B) is an orally bioavailable drug which acts as a selective and potent oxytocin receptor antagonist (Ki = 0.13 nM). It was initially developed by GlaxoSmithKline (GSK) for the treatment of premature ejaculation in men and then as an agent to enhance embryo or blastocyst implantation in women undergoing embryo or blastocyst transfer associated with in vitro fertilization (IVF)., and was also investigated for use in the treatment of adenomyosis.