Developmental Origins of Health and Disease (abbreviated DOHaD) is an approach to medical research emphasizing the role of prenatal and perinatal exposure to environmental factors, such as undernutrition, in determining the development of human diseases in adulthood. This approach includes an emphasis on epigenetic causes of adult chronic diseases, including the potential for such environmental causes to influence disease risk across generations.
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| - Developmental Origins of Health and Disease (en)
- 都哈理論 (zh)
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| - Developmental Origins of Health and Disease (abbreviated DOHaD) is an approach to medical research emphasizing the role of prenatal and perinatal exposure to environmental factors, such as undernutrition, in determining the development of human diseases in adulthood. This approach includes an emphasis on epigenetic causes of adult chronic diseases, including the potential for such environmental causes to influence disease risk across generations. (en)
- 都哈理论,即DOHaD理论(Developmental Origins of Health and Disease),直译为“健康和疾病的发育起源”学说,是指人类在早期发育过程中(包括胎儿、婴儿、儿童时期)经历不利因素(营养不良、营养过剩、激素暴露、子宫胎盘功能不良等),组织器官在结构和功能上会发生永久性或程序性改变,将会影响成年期糖尿病、代谢综合征、心血管疾病、精神行为异常、哮喘、肿瘤、骨质疏松、神经疾病等慢性非传染性疾病的发生发展。 DOHaD理论能解释人类疾病的生态模式,因此其已成为成年期慢性非传染性疾病病因研究的重要组成部分,为慢性疾病的研究提供了一个全新的视角。 (zh)
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| - Developmental Origins of Health and Disease (abbreviated DOHaD) is an approach to medical research emphasizing the role of prenatal and perinatal exposure to environmental factors, such as undernutrition, in determining the development of human diseases in adulthood. This approach includes an emphasis on epigenetic causes of adult chronic diseases, including the potential for such environmental causes to influence disease risk across generations. (en)
- 都哈理论,即DOHaD理论(Developmental Origins of Health and Disease),直译为“健康和疾病的发育起源”学说,是指人类在早期发育过程中(包括胎儿、婴儿、儿童时期)经历不利因素(营养不良、营养过剩、激素暴露、子宫胎盘功能不良等),组织器官在结构和功能上会发生永久性或程序性改变,将会影响成年期糖尿病、代谢综合征、心血管疾病、精神行为异常、哮喘、肿瘤、骨质疏松、神经疾病等慢性非传染性疾病的发生发展。 DOHaD理论能解释人类疾病的生态模式,因此其已成为成年期慢性非传染性疾病病因研究的重要组成部分,为慢性疾病的研究提供了一个全新的视角。 (zh)
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