Cygnus NG-16, previously known as Cygnus OA-16, was the sixteenth flight of the Northrop Grumman robotic resupply spacecraft Cygnus and its fifteenth flight to the International Space Station (ISS) under the Commercial Resupply Services (CRS-2) contract with NASA. The mission was launched on 10 August 2021 at 22:01:05 UTC, for a (planned) 90-day mission at the ISS. This was the fifth launch of Cygnus under the CRS-2 contract.