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Amyloid beta A4 precursor protein-binding family B member 3 is a protein that in humans is encoded by the APBB3 gene. The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.

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  • APBB3 (en)
  • APBB3 (pt)
  • APBB3 (uk)
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  • Amyloid beta A4 precursor protein-binding family B member 3 is a protein that in humans is encoded by the APBB3 gene. The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. (en)
  • APBB3 (do inglês: Amyloid beta A4 precursor protein-binding family B member 3) é uma proteína que nos humanos é codificada pelo gene com o mesmo nome. A proteína codificada por este gene é um membro da família proteíca APBB. Pode ser encontrada no citoplasma e liga-se ao domínio intracelular da (APP) assim como a outra proteína semelhantes à APP. Pensa-se que a proteína codificada por este gene possa modular a internalização da APP. Múltiplas variantes de transcriptos codificando diferentes isoformas foram encontradas para este gene. (pt)
  • APBB3 (англ. Amyloid beta precursor protein binding family B member 3) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 5-ї хромосоми. Довжина поліпептидного ланцюга білка становить 486 амінокислот, а молекулярна маса — 52 585. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
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  • Amyloid beta A4 precursor protein-binding family B member 3 is a protein that in humans is encoded by the APBB3 gene. The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. (en)
  • APBB3 (do inglês: Amyloid beta A4 precursor protein-binding family B member 3) é uma proteína que nos humanos é codificada pelo gene com o mesmo nome. A proteína codificada por este gene é um membro da família proteíca APBB. Pode ser encontrada no citoplasma e liga-se ao domínio intracelular da (APP) assim como a outra proteína semelhantes à APP. Pensa-se que a proteína codificada por este gene possa modular a internalização da APP. Múltiplas variantes de transcriptos codificando diferentes isoformas foram encontradas para este gene. (pt)
  • APBB3 (англ. Amyloid beta precursor protein binding family B member 3) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 5-ї хромосоми. Довжина поліпептидного ланцюга білка становить 486 амінокислот, а молекулярна маса — 52 585. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин Задіяний у таких біологічних процесах, як альтернативний сплайсинг, поліморфізм. Локалізований у цитоплазмі, ядрі. (uk)
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