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The antigen leukocyte antibody test (ALCAT test) is one that claims to measure adverse reactions to dietary substances. It was created by American Medical Testing Laboratories and is now marketed by Cell Science Systems (also known as ALCAT Diagnostic Systems) of Deerfield Beach, Florida.Researched conducted at Yale School of Medicine published in BMJ Open Gastroenterology in 2017 demonstrated improvement for those with irritable bowel syndrome

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  • ALCAT-Test (de)
  • ALCAT test (en)
  • Alcat test (it)
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  • Der ALCAT-Test (englisch Antigen Leukocyte Cellular Antibody Test) oder Leukozytenaktivierungstest auf Immunstimulanzien ist als zellulärer Allergen-Stimulationstest ein in der Alternativmedizin eingesetztes diagnostisches Verfahren zur qualitativen Bestimmung von Nahrungsmittelintoleranzen. Er basiert auf der Hypothese, dass Nahrungsmittelunverträglichkeiten durch eine entzündliche Reaktion gegen bestimmte Nahrungsmittel verursacht sein können. Anhand der Messung der Reaktionen des Bluts des Patienten auf eine Vielzahl von Lebensmittelextrakten und Lebensmittelzusatzstoffe wird dem Patienten nahegelegt, welche Nahrungsmittel er meiden solle. Das Verfahren bzw. dessen Aussagekraft ist wissenschaftlich nicht untermauert. (de)
  • The antigen leukocyte antibody test (ALCAT test) is one that claims to measure adverse reactions to dietary substances. It was created by American Medical Testing Laboratories and is now marketed by Cell Science Systems (also known as ALCAT Diagnostic Systems) of Deerfield Beach, Florida.Researched conducted at Yale School of Medicine published in BMJ Open Gastroenterology in 2017 demonstrated improvement for those with irritable bowel syndrome (en)
  • L'Alcat test (acronimo di antigen leukocyte cellular antibody test) è un test di laboratorio mediante il quale viene effettuata la diagnosi di intolleranza alimentare. La scienza medica non riconosce l'esistenza di queste intolleranze e ritiene tali test una truffa. Quando tale reazione si verifica ci si troverebbe in presenza di una reazione avversa all'alimento testato. (it)
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  • The antigen leukocyte antibody test (ALCAT test) is one that claims to measure adverse reactions to dietary substances. It was created by American Medical Testing Laboratories and is now marketed by Cell Science Systems (also known as ALCAT Diagnostic Systems) of Deerfield Beach, Florida.Researched conducted at Yale School of Medicine published in BMJ Open Gastroenterology in 2017 demonstrated improvement for those with irritable bowel syndrome "These findings reject the null hypothesis and show that a diet guided by leucocyte activation testing results in demonstrable clinical improvement in IBS. These clinical results, associated with a reduction in plasma neutrophil elastase, have implications for better understanding the role of food intolerance and the pathophysiology of IBS." A study conducted in 2014 demonstrated reactions identified as "severe" were associated with the up-regulation of CD11b on CD4+ and CD8+ T cells, suggesting a basis for further research into the mechanisms alleged. Research published up to 2010 did not support the test or provide evidence that it was a reliable medical diagnostic tool; since it had not been validated. In a position statement, the Australasian Society of Clinical Immunology and Allergy classified the ALCAT with other forms of cytotoxic tests as inappropriate tests, saying of them "These results have been shown to not be reproducible, give different results when duplicate samples are analysed blindly, don't correlate with those from conventional testing, and 'diagnose' food hypersensitivity in subjects with conditions where food allergy is not considered to play a pathogenic role." (en)
  • Der ALCAT-Test (englisch Antigen Leukocyte Cellular Antibody Test) oder Leukozytenaktivierungstest auf Immunstimulanzien ist als zellulärer Allergen-Stimulationstest ein in der Alternativmedizin eingesetztes diagnostisches Verfahren zur qualitativen Bestimmung von Nahrungsmittelintoleranzen. Er basiert auf der Hypothese, dass Nahrungsmittelunverträglichkeiten durch eine entzündliche Reaktion gegen bestimmte Nahrungsmittel verursacht sein können. Anhand der Messung der Reaktionen des Bluts des Patienten auf eine Vielzahl von Lebensmittelextrakten und Lebensmittelzusatzstoffe wird dem Patienten nahegelegt, welche Nahrungsmittel er meiden solle. Das Verfahren bzw. dessen Aussagekraft ist wissenschaftlich nicht untermauert. (de)
  • L'Alcat test (acronimo di antigen leukocyte cellular antibody test) è un test di laboratorio mediante il quale viene effettuata la diagnosi di intolleranza alimentare. La scienza medica non riconosce l'esistenza di queste intolleranze e ritiene tali test una truffa. Il test consiste nel mettere a contatto il sangue del paziente ottenuto con un normale prelievo con una serie di sostanze alimentari di cui si sospetta essere intolleranti. Le reazioni alla intolleranza non sempre sarebbero immediate ma si potrebbero presentare anche diverse ore dopo l'assunzione della sostanza, quindi il test evidenzierebbe una reazione avversa agli alimenti cioè agli allergeni alimentari. Tali allergeni indurrebbero modificazioni sia in numero che in dimensioni di alcune cellule ematiche del paziente in particolare dei leucociti neutrofili (granulociti neutrofili). Quando tale reazione si verifica ci si troverebbe in presenza di una reazione avversa all'alimento testato. (it)
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