The 2021–22 Belmont Bruins women's basketball team represents Belmont University during the 2021–22 NCAA Division I women's basketball season. The Bruins, led by second year head coach , play their home games at the Curb Event Center as members of the Ohio Valley Conference (OVC). They finished the season 23–8, 16–2 in OVC play win the OVC regular season. They won the OVC women's tournament by defeating Tennessee Tech and earns an automatic trip to the NCAA women's tournament where they upset Oregon in the first round before losing to Tennessee in the second round.